You did set up a kvm and have one physical interface with IP 192.168.100.121, i.e. eno1?
To get a bridge tune your /etc/network/interfaces like this:
auto lo
iface lo inet loopback
iface eno1 inet manual
auto br0
iface br0 inet static
address 192.168.100.121
netmask 255.255.0.0
gateway 192.168.100.1
dns-nameservers 192.168.100.2 8.8.8.8
dns-search inbbradio.de
bridge_ports eno1
bridge_stp off
bridge_fd 0
bridge_maxwait 0
# END
That means:
Yout establish a virtual bridge br0 with ip 192.168.100.121 and your physical interface eno1 is docked on the inner side of this bridge.
YOURLAN << br0WITH192.168.100.121<<>>YOURPHYSICALeno1